Good general health begins with good oral health

​Several international organisms recommend the use of CPC in COVID-19 prevention protocols:

• Regional Federation of Surgeons and Dentists from Lombardy (Italy)
• Dental Council of Spain

• Wuhan University (China)

These organisms recommend:

DURING THE VISIT TO THE CLINIC
CETYLPYRIDINIUM CHLORIDE (CPC) AND SCIENTIFIC EVIDENCE AGAINST SARS-CoV-2 10

 

Before beginning any intraoral exam or treatment, it is recommended that patients
use a mouthwash for 30 seconds to reduce the viral load.

 

This protocol includes the use of a mouthrinse with Cetylpyridinium Chloride.

cpc.protect.png

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receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci. 2020
Feb 24;12(1):8.
2. Rabi FA, Al Zoubi MS, Kasasbeh GA, Salameh DM, Al-Nasser AD. SARS-CoV-2 and
Coronavirus Disease 2019: What We Know So Far. Pathogens. 2020 Mar 20;9(3)
3. Wölfel R. Corman VM, Guggemos W, Seilmaier M, Zange S, Müller MA, et al.
Virological assessment of hospitalized patients with COVID-2019. Nature https://-
doi.org/10.1038/s41586-020-2196-x (2020).
4. Peng X, Xu X, Li Y, Cheng L, Zhou X, Ren B. Transmission routes of 2019-nCoV
and controls in dental practice. Int J Oral Sci. 2020 Mar 3;12(1):9
5. Liu Y, Yan LM, Wan L, Xiang TX, Le A, Liu JM, Peiris M, Poon LLM, Zhang W. Viral
dynamics in mild and severe cases of COVID-19. Lancet Infect Dis. 2020 Mar 19.
pii: S1473-3099(20)30232-

6. Popkin DL,ZilkaS,DimaanoM, Fujioka H, Rackley C,SalataR et al.Cetylpyridinium
chloride (CPC) exhibits potent, rapid activitygainstinfluenza viruses in
vitro and in vivo.PathogensandImmunity. 2017;2(2):253-69.
7. Mukherjee PK, Esper F, Buchheit K, Arters K, Adkins I, Ghannoum MAet al.
Randomized, double-blind, placebo-controlled clinical trial to assess the safety
and effectiveness of a novel dual-action oral topical formulation against upper
respiratory infections. BMC Infect Dis. 2017 Jan 14;17(1):74
8. Liang Shen, Junwei Niu, Chunhua Wang, Baoying Huang, Wenling Wang, Na
Zhu, Yao Deng, Huijuan Wang, Fei Ye, Shan Cen, Wenjie Tan. 2019. High-Throughput
Screening and Identification of Potent Broad-Spectrum Inhibitors of Coronaviruses.
Journal of Virology. doi: 10.1128/JVI.00023-19 93 (12)
9. Quirynen M, Avontroodt P, Soers C, Zhao H, Pauwels M, van Steenberghe D.
Impact of tongue cleansers on microbial load and taste. J Clin Periodontol 2004;
31: 506–510.

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